Thalassemia is a genetic condition that affects the body's ability to produce hemoglobin, the protein that carries oxygen to red blood cells throughout the body. The name thalassemia comes from the Greek word "thalassa," meaning "sea," because the condition was first identified in people living near the Mediterranean Sea. It is now known to affect people of all backgrounds and racial groups.
Thalassemia can be divided into two main categories: alpha thalassemia and beta thalassemia. Alpha thalassemia is caused by the absence of one or more of the four genes responsible for making alpha globin, a protein that helps make hemoglobin. Beta thalassemia is caused by a mutation in the gene responsible for making beta globin, another protein that helps make hemoglobin.
Depending on the severity of the condition, people with thalassemia may experience a range of symptoms. These can include anemia, jaundice, fatigue, bone deformities, enlarged spleen, and other complications. Treatment for thalassemia is available and can include blood transfusions, iron chelation therapy, gene therapy, and bone marrow transplants.
Thalassemia is an important condition to be aware of, as it can cause serious health complications if left untreated. It is important to understand the causes and symptoms of thalassemia, and to seek medical attention if you or someone you know may be affected.