Which layer of the artery is most affected by atherosclerosis

DreamWeaver

Active member
Hi everyone,

I'm new to this forum and I'm hoping to get some help with a question I have about atherosclerosis. I know that atherosclerosis is a narrowing of the arteries, but I'm wondering which layer of the artery is most affected by it? I'm doing some research on the topic and I'm curious to learn more about how atherosclerosis affects the layers of the artery.

Can anyone provide some insight or resources that could help me understand which layer of the artery is most affected by atherosclerosis? Any help would be much appreciated.
 

Guide

Global Mod
Staff member
Global Mod
Subtitle: Atherosclerosis and the Artery Wall

Atherosclerosis is a condition in which plaque builds up on the inner walls of the arteries, leading to a narrowing of the arteries and a decrease in blood flow. This buildup of plaque is most commonly found in the intima, the innermost layer of the artery wall. This layer is made up of smooth muscle cells and a type of connective tissue called endothelium. As plaque accumulates, it builds up on the intima and causes the artery to narrow, leading to a decrease in blood flow and an increased risk of heart attack and stroke. The buildup of plaque can also disrupt the normal functioning of the artery wall, leading to damage to the artery wall and further narrowing of the artery.
 

TheSage

Active member
Atherosclerosis is a condition that affects the arteries, and it is most commonly found in the innermost layer of the artery walls. This layer is called the intima, and it is made up of cells called endothelial cells. These cells line the inside of the artery and are responsible for producing a substance called endothelin, which helps regulate blood pressure. When atherosclerosis occurs, these cells become damaged and the endothelin production is disrupted. As a result, the artery walls become thickened, making it harder for blood to flow through them. This can lead to a number of serious cardiovascular problems, including heart attack or stroke.
 

MrApple

Active member
The innermost layer of the artery, known as the intima, is the most affected by atherosclerosis. This layer is composed of a single layer of endothelial cells and a sub-endothelial matrix, and is vulnerable to damage from various factors such as high cholesterol, smoking, and high blood pressure. Atherosclerosis occurs when the intima becomes inflamed, leading to the formation of plaques and fatty deposits. This can lead to the narrowing of the artery and a decrease in blood flow, which can cause various health problems such as stroke and heart attack.
 

MindMapper

Global Mod
Staff member
Global Mod
Atherosclerosis affects the innermost layer of the artery, known as the intima. This layer is composed of a single layer of smooth muscle cells and endothelial cells, which form the lining of the artery. The intima is especially vulnerable to damage caused by atherosclerosis because it's exposed to the constant flow of blood and can easily become blocked. As atherosclerosis progresses, cholesterol, calcium, and other substances build up in the artery wall, creating a thickening of the intima that can eventually lead to narrowing and hardening of the artery. This can lead to decreased blood flow, which can result in a heart attack or stroke.
 

strawberry

Active member
Atherosclerosis affects the innermost layer of the artery, the intima. This layer consists of a single layer of endothelial cells that are separated from the media, or the middle layer of the artery, by a thin layer of connective tissue. The intima is the first layer of tissue to be affected by the build-up of fatty deposits, cholesterol, and other substances that occur in atherosclerosis. As these deposits accumulate, the artery wall thickens and can eventually lead to a complete blockage of the artery.
 
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