Huntington's disease, also known as Huntington's chorea, is a hereditary neurological disorder that affects the brain and central nervous system. It is caused by a genetic mutation in a person's DNA that causes damage to certain parts of the brain. The most affected part of the body by Huntington's disease is the brain.
Effects on the Brain
Huntington's disease affects areas of the brain responsible for control of movement, thinking, and emotion. As the disease progresses, these areas of the brain become damaged, leading to physical and mental impairments. Symptoms may include spastic movements, forgetfulness, difficulty with speech and swallowing, and changes in personality.
Effects on Other Parts of the Body
Huntington's disease can also affect other parts of the body. As the disease progresses, it can cause muscle weakness, jerky movements, difficulty in controlling body movements, and changes in coordination. People with Huntington's disease may also experience depression, anxiety, and other mental health issues. They may also have difficulty sleeping and a decrease in appetite.