ALS, or amyotrophic lateral sclerosis, is a progressive neurodegenerative disorder that affects the nerve cells in the brain and spinal cord. While ALS is a distinct condition, it can be difficult to diagnose as other conditions may present similar symptoms. These include muscle diseases such as muscular dystrophy, multiple sclerosis, spinal muscular atrophy, and post-polio syndrome, as well as other neurological disorders like myasthenia gravis, Parkinson’s disease, and stroke. Certain diseases such as Lyme disease, syphilis, and heavy metal poisoning can also cause symptoms similar to ALS. It is important for patients to seek an accurate diagnosis from a qualified medical professional.