Ankylosing spondylitis is an inflammatory arthritis that primarily affects the spine. It can cause stiffness and pain in the spine, hips, and other joints. People with ankylosing spondylitis may also experience fatigue, fever, and weight loss. To diagnose ankylosing spondylitis, doctors often order a series of laboratory tests. The following are some of the most common lab tests associated with ankylosing spondylitis:
ESR (Erythrocyte Sedimentation Rate)
The erythrocyte sedimentation rate (ESR) is a blood test that measures the rate at which red blood cells settle to the bottom of a test tube. An elevated ESR indicates the presence of inflammation in the body, which is common in people with ankylosing spondylitis.
CRP (C-Reactive Protein)
C-reactive protein (CRP) is a blood test that measures the amount of inflammation in the body. An elevated CRP level is a sign of inflammation, which is common in people with ankylosing spondylitis.
HLA-B27 Antigen
The HLA-B27 antigen is a protein found on the surface of white blood cells. It is associated with ankylosing spondylitis. People with the HLA-B27 antigen have an increased risk of developing the condition.
X-Rays
X-rays are a type of imaging test that can be used to diagnose ankylosing spondylitis. X-rays can show changes in the bones and joints that are characteristic of the condition.
MRI (Magnetic Resonance Imaging)
Magnetic resonance imaging (MRI) is a type of imaging test that can provide detailed images of the spine and other organs. MRI can show the extent of damage to the spine that is caused by ankylosing spondylitis.
Blood Tests
In some cases, doctors may order a series of blood tests to look for other signs of inflammation. These may include tests for rheumatoid factor, antinuclear antibodies, and erythrocyte sedimentation rate.
Ankylosing spondylitis is a complex condition that can cause significant pain and disability. Laboratory tests can help diagnose the condition and monitor its progression. It is important to discuss your treatment options with your doctor.