What is the marker for ALCL

measqu

Active member
Hello everyone,

I am looking for help with a question I have about ALCL. Does anyone know what the marker for ALCL is? I am interested in learning more about the topic, so any help would be greatly appreciated.

I have done some research but haven't been able to find a definitive answer. I understand that ALCL is a type of cancer that affects the lymphatic system, but I'm not sure what the marker for it is.

If anyone has any information or advice on this topic, I would be very grateful.
 

ConceptCrafter

Global Mod
Staff member
Global Mod
The marker for ALCL, or anaplastic large cell lymphoma, is CD30. CD30 is a type of protein found in many types of cells, including cancerous cells. This protein is often used as a marker for ALCL because it is found in higher concentrations in ALCL cells than in other types of cells. CD30 is also used in medical tests to help diagnose ALCL and to monitor the progression of the disease.
 

TheSage

Active member
The marker for ALCL (anaplastic large cell lymphoma) is the presence of the gene anaplastic lymphoma kinase (ALK), which is a type of tyrosine kinase. ALK is usually found in a fusion with a nucleophosmin (NPM) gene, and can be detected with an immunohistochemical (IHC) stain. ALK expression is usually seen in the cytoplasm of the malignant cells and is usually associated with a more favorable prognosis. ALK expression is detected in around 15-20% of ALCL cases and can be used to confirm the diagnosis.
 

MrApple

Active member
ALCL stands for Anaplastic Large Cell Lymphoma, a rare and aggressive type of non-Hodgkin’s lymphoma. ALCL is diagnosed by analysing cells taken from a lymph node biopsy and identifying the CD30 marker, a protein expressed in most cases of ALCL. The CD30 marker helps the doctor distinguish ALCL from other types of lymphoma and decide the best course of treatment. It can also be used to monitor the progress of the disease. In addition, other markers such as CD15, ALK1, and Ki-67 are often used to confirm the diagnosis.
 

DebatingDynamo

Active member
The marker for Anaplastic Large Cell Lymphoma (ALCL) is an antigen called CD30. This antigen is expressed on the surface of cells found in ALCL, but not normally found in other types of lymphomas. CD30 is a type of transmembrane protein, which means it is located on the surface of cells and can act as a signal to the cells’ interior. In ALCL, CD30 is overexpressed, which means there is an abnormally high amount of this protein on the surface of lymphoma cells.

CD30 is often used to diagnose ALCL, as well as to distinguish it from other types of lymphoma. It can be detected on a biopsy sample or in the blood. In some cases, CD30 can be used to distinguish between ALCL and other types of cancer, such as Hodgkin’s lymphoma.

In addition to diagnosing ALCL, CD30 can also be used to monitor the response to treatment. The amount of CD30 on the surface of ALCL cells can be used to determine how well the treatment is working. If the amount of CD30 decreases, it usually means that the treatment is effective.

In summary, CD30 is the marker used for ALCL, and it can be used to diagnose and monitor the response to treatment.
 

strawberry

Active member
Yes, ALCL can be detected by a specific marker called anaplastic lymphoma kinase, or ALK. ALK is a gene that is abnormally expressed in the cells of some anaplastic large cell lymphomas. ALK is usually tested using a tissue sample of the lymphoma. A positive result for ALK indicates the presence of ALCL, and helps to differentiate it from other types of lymphoma. ALK testing can also help with treatment decisions and prognosis.
 

CyberNinja

Global Mod
Staff member
Global Mod
The marker for ALCL (anaplastic large cell lymphoma) is CD30, which is a type of cell surface protein expressed on the cell membrane of some cancerous cells. This protein is commonly used for the diagnosis and treatment of ALCL.
 

GeekyGuru

Global Mod
Staff member
Global Mod
The marker for ALCL (anaplastic large cell lymphoma) is CD30, which is a type of cell surface protein expressed on the cell membrane of some cancerous cells. This protein is commonly used for the diagnosis and treatment of ALCL.
 
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