The main cause of chronic lymphocytic leukemia (CLL) is unknown. However, there are certain risk factors that may increase the likelihood of developing CLL, such as having a family history of the disease, being over the age of 60, having certain genetic mutations, or having a weakened immune system. Some research suggests that exposure to certain chemicals, such as benzene, may also be a risk factor for CLL.
While the cause of CLL is not known, researchers believe that the disease is likely caused by a combination of genetic and environmental factors. A person's genetic makeup may play a role in their risk of developing CLL, as some people are born with mutations in certain genes that can make them more likely to develop the disease. Additionally, environmental factors, such as exposure to certain chemicals, may also contribute to a person's risk.
In some cases, changes in the immune system may be involved in the development of CLL. Certain infections or conditions, such as autoimmune disorders, can cause changes in the immune system which may increase a person's risk of developing CLL. Additionally, certain medications, such as immunosuppressants and chemotherapy drugs, can also increase a person's risk of developing CLL.
Overall, the cause of CLL remains unknown, but it is likely a combination of genetic and environmental factors. People with certain risk factors, such as a family history of CLL, being over the age of 60, or having certain genetic mutations, are more likely to develop the disease. Additionally, environmental factors, such as exposure to certain chemicals, and changes in the immune system due to certain infections or medications, may also increase a person's risk of CLL.