Alzheimer's is a progressive neurological disorder that affects an estimated 5.8 million Americans. It is marked by a gradual decline in cognitive functions, including memory, language, and thinking abilities. While there is no known cure for Alzheimer's, there is a lot of research being conducted to try to understand the root causes.
Genetic Factors
Genetic factors are believed to play a role in the development of Alzheimer's. It is estimated that up to 10 percent of people with the disease have a family history of Alzheimer's. People who carry certain gene variants, such as the ApoE4 gene, are more likely to develop the disease.
Lifestyle Factors
Lifestyle factors, such as poor diet, lack of physical activity, and smoking, may contribute to an increased risk of developing Alzheimer's. Research has found that people who eat a diet high in saturated fats and refined carbohydrates, or who do not get enough physical activity, are more likely to develop the disease.
Environmental Factors
Environmental factors, such as exposure to certain chemicals, have been linked to an increased risk of Alzheimer's. Studies have found that exposure to certain pesticides and metals, such as aluminum, can increase the risk of developing the disease.
Brain Injury
Traumatic brain injury (TBI) has been found to increase the risk of developing Alzheimer's later in life. Research has found that people who have had a TBI, especially multiple TBIs, are more likely to develop the disease.
Other Risk Factors
Other risk factors, such as age, gender, and race, can also increase the risk of developing Alzheimer's. People over the age of 65 are more likely to develop the disease, as are women. Additionally, African Americans and Hispanics are more likely to develop the disease than Caucasians.
Ultimately, the leading cause of Alzheimer's is unknown, as there are many potential contributing factors. However, research is ongoing to try to better understand the root causes of this devastating disease.