IgG is an immunoglobulin, or antibody, that is produced by the immune system. High levels of IgG can indicate a variety of conditions, including autoimmune disorders, infections, and chronic inflammation. In this article, we will discuss the causes of high IgG levels, as well as how they are diagnosed and treated.
Autoimmune Disorders
Autoimmune disorders are conditions in which the immune system mistakenly attacks the body’s own tissues and organs. These disorders can cause inflammation, which can lead to the production of IgG antibodies. Examples of autoimmune disorders that can cause high IgG levels include rheumatoid arthritis, lupus, and Hashimoto’s thyroiditis.
Infections
Infections can also cause high IgG levels. Bacterial and viral infections can stimulate the production of IgG antibodies, which can then be detected in the blood. Common infections that can cause high IgG levels include tuberculosis, Epstein-Barr virus, and cytomegalovirus.
Chronic Inflammation
Chronic inflammation can also cause high IgG levels. Chronic inflammation is a long-term inflammatory response that can occur in response to various diseases, such as cancer, and can be caused by lifestyle factors, such as smoking or a poor diet.
Diagnosis and Treatment
High IgG levels can be diagnosed through a blood test. Treatment for high IgG levels will depend on the underlying cause, but may include medications to reduce inflammation or antibiotics to treat infections. In some cases, lifestyle modifications, such as quitting smoking or changing diet, may be recommended.