Subtitle: Tests for Antiphospholipid Syndrome
Antiphospholipid Syndrome (APS) is an autoimmune disorder characterized by the formation of antiphospholipid antibodies in the blood. These antibodies can lead to blood clots, stroke, and other complications. Diagnosis of APS requires that three tests, known as the "APS triad," be performed.
Lupus Anticoagulant (LA) Test: The LA test looks for lupus anticoagulant antibodies, which are a sign of APS. This test is usually done through a blood sample.
Anticardiolipin (aCL) Antibody Test: The aCL antibody test looks for antibodies to cardiolipin, a type of phospholipid found in cell membranes. This test is usually done through a blood sample.
Beta-2 Glycoprotein 1 (β2GPI) Test: The β2GPI test looks for antibodies to beta-2 glycoprotein 1, which is a protein found in the blood. This test is usually done through a blood sample.
The results of these three tests are used to diagnose APS and to monitor the progress of the disease. If two out of the three tests are positive, a diagnosis of APS can be made. A positive LA test, along with a positive aCL antibody test, is also sufficient for diagnosis.