Autoimmune Polyendocrine Syndrome Type 1 (APS1) is an inherited disorder that is caused by a gene mutation on chromosome 21. It is characterized by the presence of multiple autoimmune conditions that affect the endocrine system, such as Addison’s disease, hypoparathyroidism, hypothyroidism, and others. The syndrome is sometimes referred to as Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED).
APS1 is the same as APS1, but the former is a more specific term for the disorder. APECED is a more general term that covers the same range of autoimmune diseases, but also includes the additional symptom of Candidiasis, an infection of the skin and mucous membranes. In addition, APECED is a more recent term, while APS1 has been used for decades.
It is important to note that APS1 and APECED are not the same as Autoimmune Polyendocrinopathy Syndrome Type 2 (APS2). APS2 is a disorder that is caused by the same gene mutation as APS1, but it is characterized by different autoimmune conditions. APS2 is characterized by the presence of autoimmune conditions such as Graves’ disease, vitiligo, alopecia, and others.
In summary, APS1 and APECED are two terms that refer to the same disorder, and they are not the same as APS2. APS1 is a more specific term for the disorder, while APECED is a more general term that includes the additional symptom of Candidiasis.