Autoimmune hemolytic anemia (AIHA) is an autoimmune disorder in which the body's immune system mistakenly attacks and destroys its own red blood cells (RBCs). In this condition, antibodies against a person's own red blood cells are produced, leading to the destruction of the cells. This results in anemia, which is a decrease in the number of red blood cells in the body, and can lead to fatigue, shortness of breath, and other symptoms.
What Causes Autoimmune Hemolytic Anemia?
Autoimmune hemolytic anemia is caused by the production of autoantibodies, which are antibodies that attack the body’s own cells. In AIHA, these autoantibodies attach to the red blood cells, causing them to be destroyed faster than they can be replaced. The exact cause of this autoantibody production is unknown, although it is thought to be related to genetics, environmental factors, and/or the body’s own immune system.
Are Antibodies Involved in Autoimmune Hemolytic Anemia?
Yes. Antibodies are involved in autoimmune hemolytic anemia, as they are the autoantibodies that attach to the red blood cells and cause them to be destroyed. Autoantibodies are proteins produced by the body’s immune system that erroneously target and attack its own cells, leading to autoimmune diseases like AIHA.