ALD, or Adrenoleukodystrophy, is a genetic disorder that affects the nervous system, adrenal glands, and white matter of the brain. It is a progressive disorder, meaning it gradually gets worse over time, and is caused by a mutation in the X-linked gene ABCD-1.
The severity of ALD varies greatly, and in some cases, it can be a lethal disorder. In severe cases, ALD can cause significant neurological complications, including blindness, seizures, and paralysis. In these cases, the eventual outcome is usually death. However, in milder cases, the symptoms may be more manageable and the long-term outlook can be more positive.
At this time, the only known cure for ALD is a hematopoietic stem cell transplant, which is usually done before the onset of severe symptoms. Unfortunately, this is not an option for everyone, as it is a complicated and risky procedure.
In conclusion, ALD can be a lethal disorder in some cases. However, the severity and prognosis of ALD varies greatly from person to person, and with proper treatment and management, individuals with ALD can lead longer, healthier lives.