A neuroendocrine tumor (NET) is a type of cancer that can be aggressive or indolent depending on certain factors. Aggressive NETs tend to grow quickly, spread to other areas of the body, and may be more difficult to treat. Indolent neuroendocrine tumors tend to grow more slowly and may not require treatment for many years.
The aggressiveness of a NET is determined by several factors, including its histology (type of tissue from which it originates), grade (how quickly the cells are multiplying), and stage (how far the tumor has spread). NETs that are classified as grade III or IV, or that have spread beyond the primary site, are considered to be more aggressive and may require more aggressive treatment.
Other factors that may influence the aggressiveness of NETs include the size of the tumor, the presence of hormone receptors, and the presence of genetic mutations. Larger tumors tend to be more aggressive, as do those with hormone receptors that can cause hormone production. Additionally, certain genetic mutations have been linked to more aggressive tumor behavior.
In general, neuroendocrine tumors can be either aggressive or indolent, depending on the type and characteristics of the tumor. Aggressive NETs may require more aggressive treatment and should be monitored closely. It is important to work with your doctor to determine the best course of treatment for your particular tumor.