Autoimmune hemolytic anemia (AIHA) is an acquired disorder in which the body's immune system mistakenly attacks its own red blood cells, resulting in anemia. Treatment for AIHA depends on the type of hemolytic anemia, the severity of symptoms, and the underlying cause.
Medications
The most common treatment for AIHA is corticosteroids, such as prednisone. Corticosteroids help reduce inflammation and suppress the immune system, allowing red blood cells to survive longer. In some cases, other immunosuppressants such as azathioprine or cyclophosphamide may be prescribed in combination with corticosteroids to further reduce inflammation and prevent the destruction of red blood cells.
Blood Transfusions
In severe cases of AIHA, a blood transfusion may be necessary to replace the destroyed red blood cells. During a blood transfusion, a patient is given donor blood that is compatible with their own. This helps to restore the body's hemoglobin levels and improve the patient's symptoms.
Immunosuppression
Immunosuppression is another form of treatment for AIHA. This type of treatment involves suppressing the immune system to prevent it from attacking the red blood cells. Immunosuppressants such as cyclosporine or mycophenolate mofetil may be used to reduce the activity of the immune system and allow red blood cells to survive longer.
Plasmapheresis
Plasmapheresis is a procedure that is sometimes used to treat AIHA. During plasmapheresis, the patient's blood is removed from the body and filtered to remove antibodies that are attacking the red blood cells. The filtered blood is then returned to the body, which helps to reduce the destruction of the red blood cells.
Splenectomy
In some cases, a splenectomy may be recommended to treat AIHA. During a splenectomy, the spleen is surgically removed from the body. The spleen is an organ that plays an important role in the body's immune system, and its removal can help reduce the destruction of red blood cells.