AML, or acute myeloid leukemia, is a type of cancer that affects the blood and bone marrow. In children, AML is treated differently than it is in adults, as the body and disease progression of a child is different from that of an adult.
The primary goal of treatment for children with AML is to achieve a remission (complete absence of signs and symptoms of the disease) with the least amount of toxicity to the body. Treatment typically consists of chemotherapy, with some cases also requiring a bone marrow transplant.
Chemotherapy is the main form of treatment for AML in children and is administered through a combination of drugs, which can be given intravenously, orally, or in pill form. These drugs work by targeting the cancer cells and preventing them from reproducing, while also minimizing damage to healthy cells. The type of chemotherapy used depends on the stage of the disease, taking into account the age of the child and any other medical conditions they may have.
In some cases, radiation therapy may also be used to target specific areas of the body where the cancer is present. This approach is used more often in adults than in children, as the radiation can have long-term effects on a child's growth and development.
In some cases, a bone marrow transplant may be necessary. This procedure involves removing healthy bone marrow from the child or a donor and replacing it with the leukemia-affected marrow. This can help to restore the child's ability to produce healthy blood cells and can improve the chances of remission.
In order to keep the disease from coming back after treatment, the child may also need to take maintenance therapy, which involves taking chemotherapy drugs for an extended period of time. This can help to reduce the risk of recurrence and keep the cancer in remission.
Treating AML in children is challenging, but with the right combination of treatments and close monitoring, it is possible to achieve remission and long-term remission.