Introduction
Pais, also known as partial androgen insensitivity syndrome, is a rare genetic disorder that affects the development of male reproductive organs. People with pais often have ambiguous genitalia and may not have periods as typical for female reproductive organs. It is important to understand the condition in order to provide appropriate medical care and support.
Causes of Pais
Pais is caused by a change in the androgen receptor gene. This gene is responsible for how cells respond to androgens, a type of male sex hormone. When there is a change or mutation in this gene, it causes some cells to be insensitive to androgens. This can lead to the partial or complete development of reproductive organs that are not typically male or female.
Signs and Symptoms of Pais
People with pais may have a variety of signs and symptoms, depending on the severity of the condition. Some common signs and symptoms include ambiguous genitalia, infertility, and a lack of menstruation. Other signs and symptoms may include abnormal breast development, a deep voice, and an inability to gain muscle mass.
Do People with Pais Have Periods?
People with pais typically do not have periods. This is because the uterus and ovaries do not develop properly due to the condition, so there is no way for the body to shed the lining of the uterus as it does during menstruation. Some people with pais may experience bleeding, however, this is usually due to other conditions such as endometriosis or a hormonal imbalance.