Do antihistamines lower blood platelets?
Overview
Antihistamines are commonly used medications that are used to treat allergies, hay fever, and other inflammatory conditions. They work by blocking the effects of histamine, a chemical released by the body during an allergic reaction. While antihistamines are generally considered safe, there is some concern that they may have an effect on blood platelets. Platelets are important for blood clotting, and their levels must be kept within a certain range in order for the body to function properly.
How Antihistamines Work
Antihistamines work by blocking the action of histamine, which is a chemical released by the body during an allergic reaction. Histamine causes inflammation, swelling, and itching, and antihistamines block the action of histamine to reduce these symptoms. Antihistamines come in both over-the-counter (OTC) and prescription forms and can be taken orally or topically.
Effects on Blood Platelets
There is some evidence that certain antihistamines may have an effect on blood platelets. Platelets are cells that are important for blood clotting, and their levels must be kept within a certain range in order for the body to function properly. A study published in the journal Clinical and Experimental Allergy in 2013 found that certain antihistamines, such as cetirizine and loratadine, may reduce the number of platelets in the blood. It is unclear why this occurs, but it is believed that these medications may interfere with the production of platelets in the bone marrow.
Risk Factors
It is important to note that these effects on platelet levels appear to be rare and usually only occur when large doses of antihistamines are taken. The risk of developing this side effect is also higher in people who are taking other medications that affect platelet levels, such as aspirin or warfarin. Therefore, it is important to talk to your doctor before taking any antihistamines if you are taking other medications.
Conclusion
In conclusion, there is some evidence that certain antihistamines may have an effect on blood platelets. However, this appears to be a rare side effect and usually only occurs when large doses of antihistamines are taken. If you are taking antihistamines, it is important to talk to your doctor about the potential risk of developing this side effect.