Transverse myelitis is a neurological disorder caused by inflammation of the spinal cord. It can be caused by a variety of factors, including viral or bacterial infections, autoimmune disorders, or drugs. In this article, we will discuss whether drugs can cause transverse myelitis.
Drug-Induced Transverse Myelitis
Drug-induced transverse myelitis is a rare but serious complication of some medications. It is typically caused by drugs that have an immune-modulating effect, such as interferon-alpha, interleukin-2, and some chemotherapy medications. Other drugs that have been associated with transverse myelitis include anticonvulsants, antibiotics, and muscle relaxants.
Symptoms of Drug-Induced Transverse Myelitis
The most common symptom of drug-induced transverse myelitis is sudden onset of pain and weakness in the legs. This can cause difficulty walking, loss of reflexes, and loss of sensation in the lower limbs. Other symptoms can include numbness, tingling, and burning sensations in the arms and legs.
Diagnosis of Drug-Induced Transverse Myelitis
If a patient has recently taken a medication known to cause transverse myelitis, a doctor will likely order a Magnetic Resonance Imaging (MRI) scan and/or a Spinal Tap (Lumbar Puncture) to assess the spinal cord. Blood tests may also be ordered to check for signs of infection or inflammation.
Treatment of Drug-Induced Transverse Myelitis
Treatment for drug-induced transverse myelitis depends on the underlying cause. In most cases, the doctor will prescribe corticosteroids to reduce inflammation and other medications to help manage symptoms. In some cases, intravenous immunoglobulin therapy may be recommended.
Conclusion
Drug-induced transverse myelitis is a rare but serious complication of some medications. It is typically caused by drugs that have an immune-modulating effect, such as interferon-alpha, interleukin-2, and some chemotherapy medications. Symptoms of drug-induced transverse myelitis include sudden onset of pain and weakness in the legs, numbness, tingling, and burning sensations in the arms and legs. Treatment for drug-induced transverse myelitis depends on the underlying cause and may include corticosteroids and immunoglobulin therapy.