Yes, in most cases, ASCUS (atypical squamous cells of undetermined significance) associated with Human Papillomavirus (HPV) can go away. ASCUS is classified as a cervical cell abnormality that is caused by HPV infection and is not a cancer. It is possible for the cells to go back to a normal state without treatment.
When women are infected with HPV, their body's immune system usually eliminates the virus on its own. However, in some cases, the virus remains in the body and can cause an abnormal Pap smear result. When this occurs, an ASCUS diagnosis is given.
In general, most women with ASCUS will be monitored closely to make sure the cells do not progress to a more serious abnormality. Usually, the cells return to a normal state, without treatment, within a few months. In some cases, however, the ASCUS cells may not go away and require further treatment.
If the ASCUS cells do not go away, your doctor may recommend a follow-up Pap smear or colposcopy to get a better look at the cells. If serious abnormalities are found, you may need to undergo additional treatment such as surgery or cryotherapy.
It is important to follow your doctor’s recommendations for follow-up tests and treatments to ensure that the ASCUS cells do not progress to a more serious abnormality.