Alzheimer's disease is a progressive neurodegenerative disorder that causes a gradual decline in memory, thinking, and behavior. In its advanced stages, it can lead to death. Although the exact cause of Alzheimer's disease is unknown, there are several factors that are believed to contribute to its development.
Genetic Factors
Research suggests that certain genetic mutations may increase the risk of developing Alzheimer's. The most common genetic risk factor for Alzheimer's is the apolipoprotein E (APOE) gene. People with two copies of the APOE gene, known as APOE4, are more likely to develop the disease than those with other forms of the gene.
Environmental Factors
Environmental factors, such as exposure to environmental toxins or head injuries, can also increase the risk of Alzheimer's. Other factors, such as lifestyle and diet, may also play a role.
Neurodegenerative Processes
Alzheimer's is caused by the buildup of abnormal proteins in the brain, leading to neurodegeneration and the death of neurons. This neurodegeneration causes a gradual decline in cognitive functions, such as memory, thinking, and behavior. Eventually, this leads to death.
Conclusion
Alzheimer's is a progressive and fatal neurodegenerative disorder. Although the exact cause of Alzheimer's is unknown, there are several factors that are believed to contribute to its development, such as genetics, environmental factors, and neurodegenerative processes.