Pemphigus is a rare and potentially life-threatening autoimmune disorder that affects the skin and mucous membranes. People of all ages, genders, and races can get pemphigus, but it is more common in middle-aged adults.
Symptoms of Pemphigus
The most common symptom of pemphigus is blisters or sores on the skin and mucous membranes. These blisters and sores can be very painful and can lead to infections if not treated promptly. Other common symptoms include itching, redness, swelling, and pain.
Causes of Pemphigus
The exact cause of pemphigus is unknown. However, research suggests that it is likely caused by a combination of genetic and environmental factors.
Diagnosis of Pemphigus
Pemphigus is usually diagnosed based on a physical examination, skin biopsy, and laboratory tests. A skin biopsy involves taking a small sample of skin and examining it under a microscope. Laboratory tests may include a complete blood count (CBC), blood chemistry analysis, and an immunofluorescence test.
Treatment of Pemphigus
Treatment for pemphigus is usually aimed at reducing inflammation and controlling the body’s immune system. Medications such as corticosteroids, immunosuppressants, and other immunomodulating agents may be used to control the disease. In some cases, surgery may be necessary to remove affected skin or to repair damaged tissue.