Fatigue is a common symptom of many types of cancer, including leukemia, lymphoma, and multiple myeloma. Leukemia is a cancer of the blood and bone marrow, and is often accompanied by fatigue, loss of appetite, fever, weight loss, and night sweats. Lymphoma is a cancer of the lymphatic system, and can cause fatigue, fever, night sweats, weight loss, and swollen lymph nodes. Multiple Myeloma is a cancer of the plasma cells, and often results in fatigue, bone pain, anemia, and recurrent infections. Treatment for any type of cancer can also cause fatigue, so it is important to discuss any symptoms with your doctor.