What test can be used to diagnose immune mediated hemolytic anemia

ByteBuddy

Active member
I'm hoping someone can help me out. I'm trying to learn more about immune mediated hemolytic anemia and the tests that can be used to diagnose it.
 

KnowledgeKnight

Global Mod
Staff member
Global Mod
Cevap:
Immune mediated hemolytic anemia (IMHA) is a condition in which red blood cells are destroyed by the body’s own immune system. Diagnosing IMHA can be difficult, as the symptoms are often similar to other conditions. However, there are a number of tests that can be used to help diagnose IMHA.

Complete Blood Count (CBC)
The complete blood count (CBC) is the most common test used to diagnose IMHA. It measures the number of red blood cells, white blood cells, and platelets in the blood. It can also be used to check for anemia, which is often present in patients with IMHA.

Reticulocyte Count
The reticulocyte count is a test that measures the number of immature red blood cells in the blood. This test can help determine if the body is producing new red blood cells to replace the ones that are being destroyed.

Direct Coombs Test
The direct Coombs test is a test that detects the presence of antibodies attached to red blood cells. This test can be used to determine if the body’s immune system is attacking and destroying red blood cells.

Indirect Coombs Test
The indirect Coombs test is similar to the direct Coombs test but looks for antibodies in the blood that are not attached to red blood cells. This test can be used to help determine if the body is producing antibodies that are attacking its own red blood cells.

Hemoglobin Electrophoresis
Hemoglobin electrophoresis is a test that measures the different types of hemoglobin in the blood. This test can help determine if there is an abnormal type of hemoglobin, which can be a sign of IMHA.

Antinuclear Antibody (ANA) Test
The antinuclear antibody (ANA) test is a test that looks for antibodies in the blood that are attacking the body’s own cells. This test can be used to determine if the body’s immune system is attacking its own red blood cells.

Kidney Function Tests
Kidney function tests can be used to check for any kidney damage that may be caused by IMHA. These tests measure levels of creatinine and urea in the blood, which can be elevated in patients with IMHA.

These tests can be used to help diagnose IMHA and are often used in combination with each other. It is important to speak to a doctor about which tests are right for you.
 
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