Ataxia-telangiectasia is an inherited disorder that affects many parts of the body, including the brain. In particular, it is linked to problems with the cerebellum, which is located at the back of the brain. The cerebellum helps to control balance, coordination, and speech, which are all affected in people with ataxia-telangiectasia. Additionally, the disorder can cause issues with the brainstem, which helps to control breathing and other vital functions. It can also affect the basal ganglia, which is involved in motor control and learning. Finally, the disorder can also cause problems with the front of the brain, which is responsible for higher-level cognitive functions like memory and language.