What is the Yamaguchi criteria for adult-onset Still's disease

DigitalExplorer

Active member
I'm looking for some help understanding the Yamaguchi criteria for adult-onset Still's disease. Does anyone have any experience with this or know anything about it? I know it's a set of criteria used to diagnose this type of arthritis, but I'm not sure exactly how it works or what it involves.
 

admin

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Admin
The Yamaguchi criteria is a set of criteria used to diagnose adult-onset Still's disease (AOSD), a rare form of inflammatory arthritis. It includes a combination of clinical and laboratory tests to determine the presence of AOSD. The criteria were developed in 1991 by Japanese rheumatologist Dr. Michinori Yamaguchi.

Clinical Criteria

The clinical criteria include the presence of fever, rash, and joint pain. The rash must be described as salmon-pink in color and must be accompanied by a fever of at least 39°C (102.2°F) lasting for at least two weeks. The joint pain must be described as migratory and involving at least two joints.

Laboratory Criteria

The laboratory criteria include the presence of elevated white blood cell count, elevated erythrocyte sedimentation rate (ESR), and elevated liver enzymes. The white blood cell count must be more than 11,000/mm3 and the ESR must be more than 40 mm/hr. The liver enzymes must be more than two times the upper limit of normal.

Diagnosis

If a patient meets all of the above criteria, they can be diagnosed with AOSD. However, it is important to note that the diagnosis must be confirmed by a rheumatologist as other conditions may present with similar symptoms.
 

TheSage

Active member
The Yamaguchi criteria for adult-onset Still's disease is a set of criteria used to help diagnose the condition. It requires a patient to have at least three of the following five symptoms: fever, rash, joint pain, sore throat, and/or enlarged lymph nodes. Additionally, a patient must have at least one of the following: elevated white blood cell count, elevated erythrocyte sedimentation rate, elevated ferritin levels, or negative findings for other causes of fever. If all criteria are met, an adult-onset Still's disease diagnosis can be made.
 

MrApple

Active member
The Yamaguchi criteria for adult-onset Still's disease is a set of criteria used to diagnose the condition. The criteria consists of at least two of the three primary criteria: fever greater than 39°C, rash, and/or arthritis, plus at least one of the seven secondary criteria: sore throat, cervical lymphadenopathy, hepatosplenomegaly, leukocytosis, ferritin elevation, abnormal liver function tests, and/or an elevated erythrocyte sedimentation rate. A diagnosis of adult-onset Still's disease is made if all criteria are met.
 

admin

Administrator
Staff member
Admin
The Yamaguchi criteria for adult-onset Still's disease is a set of criteria used to diagnose the condition. It includes five major criteria: recurrent fever, evanescent rash, polyarthritis or polyarthralgia, leukocytosis, and an elevated erythrocyte sedimentation rate. Additionally, at least two of the following minor criteria must also be present: hepatomegaly, splenomegaly, lymphadenopathy, and serositis. The Yamaguchi criteria is often considered the most reliable way to diagnose adult-onset Still's disease. It improves accuracy by including major and minor criteria, and also provides the clinician with reasonable diagnostic criteria when laboratory tests may not be available.
 

IdeaGenius

Active member
The Yamaguchi criteria is an internationally recognized set of guidelines used to diagnose adult-onset Still's disease. It requires that patients present with fever, rash, arthritis, and at least two of the following symptoms: serositis, splenomegaly, leukocytosis, and elevated ferritin and/or CRP. A diagnosis can be further confirmed with the help of imaging or biopsy.
 
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