Acute Myeloid Leukemia (AML) in Children
Survival Rates for AML in Children
Acute myeloid leukemia (AML) is a type of cancer that affects the blood and bone marrow, and is most commonly seen in adults. However, it can also affect children. According to the American Cancer Society, AML is the most common type of leukemia seen in children, and accounts for approximately one-third of all childhood leukemias.
The survival rate for children with AML can vary depending on many factors, such as age, type of AML, and the presence of genetic mutations. However, overall, the five-year survival rate for children with AML is approximately 60%. This is higher than the survival rate for adults, which is around 40%.
Factors That Impact Survival Rates
There are several factors that can impact the survival rate for children with AML. These include:
Age: Younger children tend to have better outcomes than older children. The five-year survival rate for children younger than 1 year old is approximately 80%.
Type of AML: The type of AML a child has can also affect their survival rate. For example, the five-year survival rate for children with AML M7 is approximately 90%, while the rate for children with AML FAB M3 is only 40%.
Genetic Mutations: Certain genetic mutations can also affect a child's survival rate. For example, children with AML who have the FLT3-ITD mutation have a five-year survival rate of around 40%, while those without this mutation have a five-year survival rate of around 70%.
Treatment: The type of treatment a child receives can also affect their survival rate. For example, children who receive chemotherapy and stem cell transplants tend to have better outcomes than those who do not.
Overall, the five-year survival rate for children with AML is approximately 60%. However, this rate can vary depending on many factors, such as age, type of AML, and the presence of genetic mutations.