Autoimmune diseases are typically diagnosed by a combination of physical exams, medical history, lab tests, imaging studies, and biopsies. To begin, the doctor will review your medical history and conduct a physical exam, looking for signs of an autoimmune disease. Depending on the suspected illness, they may then order lab tests such as a complete blood count, sedimentation rate, urinalysis, or antibody tests. Imaging studies such as X-rays, CT scans, MRI scans, and ultrasound may also be used to help diagnose the condition. A tissue biopsy may also be conducted to confirm the diagnosis. Lastly, a doctor may also order additional tests to rule out other conditions or to identify the specific autoimmune disease.