What is the pathophysiology of Adie's pupil

[CuriousCat]

I'm hoping to find some help with understanding the pathophysiology of Adie's pupil. I recently read about this condition, and it's quite confusing to me. Does anyone have any experience with Adie's pupil and can explain the pathophysiology behind it? I would be really appreciative of any insight or advice you can provide! Thank you.

 

[Guide]

Adie's pupil, also called tonic pupil, is a condition characterized by an abnormally slow or sluggish pupillary response to light and near stimulus, and a reduced or absent reaction to accommodation. It is usually caused by damage to the postganglionic parasympathetic nerve fibers that innervate the pupillary constrictor muscles.

Pathophysiology

Adie's pupil is caused by damage to the postganglionic parasympathetic nerve fibers that innervate the pupillary constrictor muscles, resulting in an abnormally slow or sluggish pupillary response to light and near stimulus, and a reduced or absent reaction to accommodation. The underlying cause of Adie's pupil is unknown, but it can be associated with viral infections, autoimmune diseases, head injuries, brain tumors, and certain medications.

Diagnosis

Adie's pupil is typically diagnosed by physical exam. The doctor will examine the pupil size and response to light and near stimuli. If the pupil is abnormally sluggish or does not constrict when focusing on near objects, Adie's pupil may be diagnosed.

Treatment

Adie's pupil is usually a benign condition that does not require treatment. If the pupil constricts slowly but the patient is asymptomatic, no treatment is needed. If the patient has persistent symptoms, such as blurred vision, eye strain, or difficulty focusing, the doctor may prescribe eyedrops to help constrict the pupil.

 

[TheSage]

Adie's pupil, otherwise known as tonic pupil, is an abnormality of the pupil which results from a lesion of the parasympathetic nerve fibres that control the pupil. This lesion results in an impaired response to light, causing the pupil to be dilated and unresponsive. Additionally, the pupil doesn't react to near-accommodation, and there may be an absence of the consensual light reflex. The underlying cause of Adie's pupil is unknown, but it is believed to be caused by an autoimmune disorder, viral infection, or a traumatic injury.

 

[MrApple]

Adie's pupil, also known as tonic pupil, is a disorder of the autonomic nervous system that is characterized by an abnormally slow or absent pupillary response to light. The cause of Adie's pupil is unknown, but it has been linked to viral infections, trauma, toxins, and autoimmune disorders. Pathophysiologically, Adie's pupil is thought to be caused by damage to the iris sphincter muscle, the nerve fibers that control the muscle, or a combination of both. This damage disrupts the normal balance between parasympathetic and sympathetic fibers, resulting in abnormal pupil dilation.

 

[ByteBuddy]

Adie's pupil, also known as tonic pupil, is a condition in which the pupil of the eye fails to constrict when exposed to bright light. This condition is caused by damage to the parasympathetic nerve innervating the eye, resulting in an imbalance of the sympathetic and parasympathetic systems within the eye. As a result, the pupil fails to constrict, leading to a dilated pupil, and is unable to react to light changes. This condition can also lead to decreased pupil reactivity when exposed to a near object and decreased accommodation, which is the ability of the eye to focus on a close object.

 

[CyberNinja]

Adie's pupil, also known as Holmes-Adie Syndrome, is a condition caused by a lesion in the oculomotor nerve, resulting in an abnormally dilated pupil which is non-reactive to light. In addition, the affected pupil exhibits a slow constriction response to accommodation and may have an abnormal near-reflex. Unilateral or bilateral involvement is possible, and the etiology is thought to be of an idiopathic nature.