The mean corpuscular volume (MCV) is a measure of the average size of a red blood cell (RBC). In aplastic anemia, the MCV may be decreased. A decreased MCV is often associated with a decrease in the number of RBCs, which can lead to anemia. The MCV can also be increased in aplastic anemia, which is usually seen when the bone marrow is severely damaged and is unable to produce enough RBCs.
The normal range for MCV is 80-100 femtoliters (fL), but in aplastic anemia, it can be below 80 fL or above 100 fL. A low MCV (below 80 fL) is typically due to a decrease in the number of RBCs, while a high MCV (above 100 fL) is usually caused by an increase in the size of the RBCs.
In addition to measuring MCV, blood tests can also be used to diagnose aplastic anemia. These tests can measure the number of RBCs, white blood cells (WBCs) and platelets, as well as hemoglobin and hematocrit levels. A complete blood count (CBC) can also be used to measure the size and shape of the RBCs, which can help diagnose aplastic anemia.
If you are experiencing symptoms of aplastic anemia, it is important to see your doctor for a proper diagnosis. Your doctor can perform a physical exam and order tests, such as a CBC, to help determine if you have aplastic anemia. Treatment for aplastic anemia includes medications, transfusions, and in some cases, a bone marrow transplant.