Laboratory diagnosis of pancreatitis involves testing for elevated amylase and lipase levels, as well as other markers of pancreatic inflammation such as serum immunoglobulins or C-reactive protein. Imaging tests such as abdominal ultrasonography or computed tomography scan can also be used to identify signs of pancreatic inflammation.
Elevated Amylase and Lipase Levels
Elevated amylase and lipase levels in the blood are the most common tests used to diagnose pancreatitis. Amylase is an enzyme produced by the pancreas that helps break down carbohydrates. Lipase is an enzyme produced by the pancreas that helps break down fats. When the pancreas becomes inflamed, these enzymes leak into the blood stream. Elevated levels of amylase and lipase in the blood can indicate pancreatitis.
Serum Immunoglobulins
Serum immunoglobulins are proteins produced by the immune system in response to inflammation. They can be measured in the blood to determine the presence of inflammation. Elevated levels of immunoglobulins in the blood can indicate pancreatitis.
C-Reactive Protein
C-reactive protein (CRP) is a protein produced by the liver in response to inflammation. It can be measured in the blood to determine the presence of inflammation. Elevated levels of CRP in the blood can indicate pancreatitis.
Imaging Tests
Imaging tests such as abdominal ultrasonography or computed tomography scan can also be used to identify signs of pancreatic inflammation. These tests can detect changes in the size and shape of the pancreas, changes in the composition of the pancreas, and the presence of fluid in the pancreas.