The gold standard investigation for acute pancreatitis is a clinical diagnosis that is made after ruling out other causes of abdominal pain. This typically includes a combination of clinical signs and symptoms along with laboratory tests and imaging.
Clinical signs and symptoms
The most common clinical signs and symptoms of acute pancreatitis include abdominal pain, fever, nausea, vomiting, and jaundice. Patients may also present with abdominal tenderness, jaundice, and elevated levels of amylase and lipase in the blood.
Laboratory tests and imaging
Laboratory tests for acute pancreatitis include tests for amylase and lipase, as well as a complete blood count (CBC) and liver function tests. Imaging tests for acute pancreatitis include abdominal ultrasound, computed tomography (CT) scan, and magnetic resonance imaging (MRI).
Diagnosis
Based on the clinical signs and symptoms, laboratory tests, and imaging tests, the diagnosis of acute pancreatitis can be made. Treatment typically involves supportive care, including fluids, antibiotics, and pain control. In severe cases, surgery may be necessary.