Clinical examination of hemolytic anemia is a diagnostic procedure that looks for signs and symptoms of the condition. It includes physical examination, laboratory tests, imaging tests, and other specialized tests.
Physical Examination
During a physical examination, the doctor will look for signs of hemolytic anemia such as jaundice (yellowing of the skin and eyes), pale skin, and enlarged spleen. The doctor will also take the patient's vital signs, such as blood pressure and heart rate, and examine the patient's eyes, skin, and lymph nodes.
Laboratory Tests
Laboratory tests are used to diagnose hemolytic anemia. These tests include a complete blood count (CBC), which measures the levels of red blood cells, white blood cells, and platelets in the blood; a reticulocyte count, which measures the number of immature red blood cells in the blood; and a hemoglobin electrophoresis test, which looks at the type of hemoglobin in the blood.
Imaging Tests
Imaging tests may also be used to diagnose hemolytic anemia. These tests include an ultrasound of the abdomen, which can detect an enlarged spleen, and a bone marrow biopsy, which can show if the bone marrow is producing too many red blood cells.
Specialized Tests
Specialized tests may also be used to diagnose hemolytic anemia. These tests include a direct antiglobulin test (DAT), which can detect if the patient’s red blood cells are being destroyed by antibodies; a Coombs test, which can detect if the patient has an autoimmune disorder; and a hemoglobin solubility test, which can detect if the patient’s hemoglobin is abnormal.
