The #1 root cause of Alzheimer's is not yet known. However, scientists believe that a combination of genetic, environmental, and lifestyle factors may be involved. Genetics, especially the presence of certain gene mutations, may increase a person's risk of developing the condition. Environmental factors, such as exposure to certain toxins, can also play a role. Finally, lifestyle factors, such as diet, exercise, and stress levels, may contribute to Alzheimer's development.
Genetic Factors
Genetics plays an important role in the development of Alzheimer's disease. A number of gene mutations have been identified that may increase a person's risk of developing the condition. The most common of these is the apolipoprotein E (APOE) gene. Mutations in this gene are associated with an increased risk of developing late-onset Alzheimer's. Other genes, such as the amyloid precursor protein (APP) gene, have also been implicated in the development of Alzheimer's.
Environmental Factors
Environmental factors, such as exposure to certain toxins, may also increase a person's risk of developing Alzheimer's. For example, research suggests that exposure to lead or other metals can increase the risk of developing the condition. Additionally, pesticides and other chemicals may increase the risk of Alzheimer's.
Lifestyle Factors
Lifestyle factors, such as diet, exercise, and stress levels, may also play a role in the development of Alzheimer's. Eating a healthy diet, exercising regularly, and managing stress can reduce the risk of developing the condition. Additionally, staying socially active and engaging in mentally stimulating activities can help protect against Alzheimer's.