Stage 3 autoimmune hepatitis (AIH) is a severe form of autoimmune liver disease. It is caused by an overactive immune system that attacks the liver, resulting in inflammation and damage to the organ. AIH is a progressive disease and is divided into three stages. Stage 3 is the most serious stage and is characterized by advanced liver inflammation and scarring, known as cirrhosis.
People with stage 3 AIH may experience a variety of symptoms, including fatigue, jaundice, abdominal pain, nausea, and weight loss. Other symptoms may include ascites (accumulation of fluid in the abdomen), itching, and confusion. As the liver damage progresses, scarring can lead to portal hypertension (high blood pressure in the portal vein) and other complications.
Treatment for stage 3 AIH typically includes a combination of immunosuppressive medications, such as prednisone, azathioprine, and cyclosporine. In some cases, a liver transplant may be necessary. The goal of treatment is to reduce inflammation and slow the progression of liver damage.
It is important for people with stage 3 AIH to take steps to reduce the risk of further damage to the liver. This includes avoiding alcohol and following a healthy diet. Regular monitoring by a doctor is also important, as AIH can be difficult to diagnose and can progress quickly.