Madelung's disease, also known as benign symmetric lipomatosis, is a rare disorder that is characterized by the abnormal accumulation of fat deposits in the neck, shoulder, and upper arm regions. It is caused by an overproduction of the hormone leptin, which is responsible for regulating fat storage in the body. Treatment typically involves physical therapy, diet modification, and, in extreme cases, surgery. In addition, medications such as metformin and orlistat can be used to help reduce the amount of fat in the body. It is important to note that Madelung's disease is not life-threatening, and with proper management and lifestyle changes, individuals with this condition can lead a normal life.