Hemolytic anemia is an umbrella term for a group of blood disorders in which the body's red blood cells are destroyed faster than they can be produced. This leads to a decrease in the number of red blood cells in circulation, resulting in anemia. Hemolytic anemia can be caused by a variety of underlying conditions, including autoimmune disorders, inherited genetic disorders, infections, and toxic exposures.
Causes of Hemolytic Anemia
Hemolytic anemia can be caused by a variety of underlying conditions, including autoimmune disorders, inherited genetic disorders, infections, and toxic exposures.
Autoimmune Disorders: In some cases, the body’s immune system mistakenly attacks and destroys its own red blood cells. This type of autoimmune hemolytic anemia can be caused by a variety of conditions, including lupus, rheumatoid arthritis, scleroderma, and certain types of cancer.
Inherited Genetic Disorders: Some people are born with genetic mutations that cause their bodies to produce red blood cells that are fragile and easily destroyed. This type of hemolytic anemia is known as a hereditary hemolytic anemia and can be caused by disorders such as thalassemia and sickle cell anemia.
Infections: Certain types of infections, such as malaria, can cause the destruction of red blood cells. This type of hemolytic anemia is known as infectious hemolytic anemia.
Toxic Exposures: In some cases, exposure to toxic substances such as certain medications or chemicals can lead to the destruction of red blood cells. This type of hemolytic anemia is known as toxic hemolytic anemia.
Symptoms of Hemolytic Anemia
The symptoms of hemolytic anemia can vary depending on the underlying cause. Common symptoms include fatigue, shortness of breath, jaundice (yellowing of the skin and eyes), and dark-colored urine.
Treatments for Hemolytic Anemia
The treatment for hemolytic anemia depends on the underlying cause. Treatments may include medications, transfusions, and lifestyle changes. In some cases, a bone marrow transplant may be recommended.