Acromegaly is a condition that is caused by an excess of growth hormone (GH) in the body. The most common cause of this condition is a tumor on the pituitary gland, which is located at the base of the brain. If left untreated, acromegaly can lead to serious health complications, such as heart disease, diabetes, and joint and bone problems. Early diagnosis and treatment of acromegaly are essential for good health outcomes.
Signs and Symptoms of Acromegaly
The signs and symptoms of acromegaly can vary from person to person. Common signs and symptoms include:
• Enlarged hands, feet, and facial features
• Abnormal growth of bones and soft tissue, such as the jaw, forehead, nose, and tongue
• Thickening of the skin
• Excessive sweating
• High blood pressure
• Fatigue
• Headaches
• Joint pain
• Carpal tunnel syndrome
• Enlarged organs, such as the heart and kidneys
• Diabetes
• Vision problems
Diagnosis of Acromegaly
Early diagnosis of acromegaly is key to successful treatment. Diagnosis usually begins with a physical exam and a review of your medical history. Your doctor may also order laboratory tests, such as blood and urine tests, to measure growth hormone and insulin-like growth factor (IGF-1) levels. Imaging tests, such as an MRI or CT scan, may also be ordered to determine the size and location of any tumors on the pituitary gland.
Treatment of Acromegaly
Treatment of acromegaly typically involves a combination of medications and surgery. Medications, such as somatostatin analogs, can help reduce GH levels and reduce tumor size. Surgery is usually recommended to remove any tumors on the pituitary gland. Radiation therapy may be used to shrink tumors that are too large to be removed with surgery.
Acromegaly is a serious condition that can lead to serious health complications if left untreated. Early diagnosis and treatment are essential for good health outcomes. If you have any of the signs or symptoms of acromegaly, talk to your doctor right away.