Adenomatoid odontogenic tumor (AOT) is an uncommon, benign odontogenic tumor that typically occurs in the anterior maxilla and mandible. It is believed to be of odontogenic epithelial origin and has a predilection for the crown portion of the maxillary central incisors. AOT is usually asymptomatic and presents as a slow-growing, well-circumscribed, radiolucent lesion that can be easily misdiagnosed as a dentigerous cyst. Histopathologically, AOT is composed of an admixture of squamous and cuboidal cells, and it is usually surrounded by a fibrous capsule.
Clinically, AOT can be diagnosed based on its characteristic radiographic appearance, which includes a well-defined, round-to-oval radiolucency that is associated with a unilocular or multilocular pattern. The lesion may also be associated with enamel and dentin formation, a radiopaque rim, and/or root resorption.
Treatment for AOT typically involves enucleation and curettage of the lesion, with or without adjunctive chemotherapy. The prognosis is generally good, and recurrence is rare. Regular follow-up is recommended to monitor for any changes in the lesion.