Acromegaly is a disorder of the skeletal system characterized by the overproduction of growth hormone (GH) from the pituitary gland. This results in abnormal growth and enlargement of the hands, feet, face, and other parts of the body. The condition is caused by a noncancerous tumor on the pituitary gland, which leads to excessive production of GH. It is important to note that acromegaly is a rare disorder, with only about 6 out of every 1 million people in the United States affected.
The most common symptoms of acromegaly include enlargement of the hands and feet, enlargement of the lower jaw, and facial features such as a prominent forehead, enlarged nose, and thicker lips. There may also be an increase in body hair, particularly on the face and torso. Other symptoms can include headaches, joint pain, fatigue, and vision problems.
The long-term effects of acromegaly can be serious and may include an increased risk of cardiovascular disease, diabetes, osteoarthritis, and a greater likelihood of developing colon cancer. If left untreated, acromegaly can lead to decreased life expectancy.
Treatment for acromegaly typically involves a combination of medications to reduce the levels of GH in the body, as well as surgery to remove the tumor from the pituitary gland. In some cases, radiation therapy may also be used. It is important to note that treatment for acromegaly may not cure the condition, but it can help to manage the symptoms and reduce the risk of complications.