When a pancreas transplant is performed, the body's immune system may reject the new organ. This is called rejection, and it is a normal response that occurs when the body perceives something foreign. Rejection occurs when the body's immune system attacks the new organ as if it were a threat.
Symptoms of Rejection
If your body rejects a pancreas transplant, you may experience a variety of symptoms. These can include fever, chills, abdominal pain, nausea, vomiting, loss of appetite, and changes in urine output. In some cases, the body may reject the pancreas to the point where it is no longer functioning.
Treatment for Rejection
If your body rejects a pancreas transplant, there are treatments available to help. The treatment will depend on the severity of the rejection. Mild rejection can usually be treated with medications to suppress the immune system. Severe rejection may require additional treatments such as intravenous immunoglobulin therapy or plasmapheresis.
Prevention of Rejection
The best way to prevent rejection is to follow your doctor's instructions carefully. This includes taking medications as prescribed, eating a healthy diet, exercising regularly, and avoiding smoking and alcohol. It is also important to attend regular follow-up appointments with your doctor to monitor for signs of rejection.
Prognosis
The prognosis for a successful pancreas transplant is good, but rejection is still a risk. With proper care and treatment, most people who have had a pancreas transplant are able to lead normal, healthy lives.