Subtitle Forum: What Drugs Are Approved for Autoimmune Hemolytic Anemia?
Autoimmune hemolytic anemia (AIHA) is a condition in which the body's immune system attacks and destroys its own red blood cells. This can lead to anemia, fatigue, and other complications. Treatment for AIHA typically includes medications to suppress the immune system, such as corticosteroids, and drugs to help the body make more red blood cells. Here are some of the drugs that are approved for the treatment of AIHA:
Corticosteroids: Corticosteroids, such as prednisone, are the most commonly prescribed medications for AIHA. They work by suppressing the immune system and reducing inflammation. They can be taken orally or intravenously.
Immunosuppressants: Immunosuppressants, such as cyclophosphamide or azathioprine, are drugs that prevent the body's immune system from attacking the red blood cells. They can be taken orally or intravenously.
Blood Transfusions: In some cases, a blood transfusion may be necessary to replace lost red blood cells. This is typically done as a last resort when other treatments have failed.
Intravenous Immunoglobulin (IVIG): IVIG is a solution made from donated blood that contains antibodies that can help to suppress the immune system and reduce inflammation. It is typically given as an infusion.
Rituximab: Rituximab is an antibody that targets a protein found on the surface of B cells, which are a type of white blood cell involved in the immune response. It can help to reduce the body's production of antibodies that attack the red blood cells.
Danazol: Danazol is a synthetic hormone that can reduce the amount of antibodies produced by the body. It is typically taken orally.
Eculizumab: Eculizumab is an antibody that can block the activity of a protein called C5, which is involved in the destruction of red blood cells. It is typically given as an intravenous infusion.
Therapies: Other therapies, such as phototherapy or plasmapheresis, may be used in some cases to help reduce the symptoms of AIHA.
