Being HPV negative but having ASCUS means that while the person has tested negative for the Human Papillomavirus (HPV), they have an abnormal Pap smear result. The acronym ASCUS stands for Atypical Squamous Cells of Undetermined Significance. This means that during a Pap smear test, the cells in the cervix that were tested were not normal but the cause of the abnormality could not be determined.
It is important to note that HPV is a virus that is sexually transmitted, and that certain strains of HPV can cause abnormal cell changes in the cervix, which can lead to cervical cancer. A Pap smear test looks for abnormal cells in the cervix that could be caused by HPV.
The presence of ASCUS on a Pap smear indicates that the cells in the cervix are not normal, but the cause of the abnormality is not known. Therefore, it is possible that the person may have an HPV infection that has not yet caused any cell changes in the cervix.
In some cases, a person with ASCUS may be asked to have follow-up testing with an HPV test to determine if HPV is present, or to have a repeat Pap smear to see if the cell changes have progressed. In other cases, the ASCUS may be due to other causes such as inflammation or infection, and no further testing may be necessary.
It is important to discuss any abnormal Pap smear results with a healthcare provider, as they can provide the best advice regarding appropriate follow-up testing or treatment options.