IgG deficiency is a condition in which the body does not produce enough of the antibody IgG, also known as immunoglobulin G. IgG is an important part of the immune system and helps protect the body from infections. Without enough IgG, a person is more likely to get infections, especially bacterial infections.
The exact cause of IgG deficiency is unknown, but it is believed to be a genetic disorder, so it is often seen in people who have a family history of the condition. In some cases, IgG deficiency can be acquired due to certain medical conditions, such as HIV/AIDS, celiac disease, or certain metabolic disorders.
The symptoms of IgG deficiency vary depending on the severity of the condition, but can include recurrent infections, such as ear infections, sinus infections, or pneumonia. In some cases, a person may also experience fatigue, muscle aches, joint pain, and swollen lymph nodes.
Diagnosis of IgG deficiency is done through a blood test, which measures the levels of IgG in the blood. If the levels are found to be lower than normal, the diagnosis of IgG deficiency is made.
Treatment for IgG deficiency typically involves boosting the immune system with medications, such as antibiotics or immunoglobulin injections. These medications help to increase IgG levels in the body and can help reduce the risk of infections. In some cases, IgG replacement therapy may also be recommended.
Overall, IgG deficiency is a condition in which the body does not produce enough of the antibody IgG, resulting in an increased risk of bacterial infections. The exact cause is unknown, but it is believed to be a genetic disorder. Diagnosis is done through a blood test and treatment typically involves boosting the immune system with medications.