Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease, is a progressive neurological disease that affects the nerve cells in the brain and spinal cord. The cause of ALS is still unknown, however, research suggests that a combination of genetic and environmental factors may play a role in its development.
One particular deficiency that may contribute to the development of ALS is an abnormal accumulation of copper in the brain and spinal cord. Copper is an essential nutrient for healthy nerve functioning, however, too much copper in the body can be toxic and can cause damage to the nerves. Studies have shown that individuals with ALS often have higher levels of copper in their brain and spinal cord compared to healthy individuals. Additionally, individuals with mutations in the gene SOD1, which is associated with ALS, have been found to have higher levels of copper accumulation in the brain and spinal cord compared to those without mutations.
Other deficiencies that have been associated with ALS include a deficiency in vitamin D, which is an important nutrient for maintaining healthy nerve cells. Low levels of vitamin D have been linked to a higher risk of developing ALS. Additionally, a deficiency in antioxidants, such as Vitamin C and E, may also contribute to the development of ALS. Antioxidants help protect nerve cells from damage, and individuals with ALS have been found to have lower levels of antioxidants in their bodies compared to healthy individuals.
Finally, a deficiency in the trace mineral selenium may also be linked to ALS. Selenium is an essential nutrient for nerve health, and individuals with ALS have been found to have lower levels of selenium in their bodies compared to healthy individuals.
Overall, while the exact cause of ALS is still unknown, research suggests that a deficiency in certain nutrients, such as copper, vitamin D, antioxidants, and selenium, may play a role in the development of the disease.