Huntington's disease is a fatal, progressive neurological disorder caused by a genetic mutation. The mutated gene is responsible for producing a protein called huntingtin, which is necessary for normal brain function. When the gene is mutated, too much of the huntingtin protein is produced, leading to the death of brain cells and the deterioration of muscle control and cognitive function.
Death from Huntington’s disease is typically caused by a combination of the physical and cognitive decline associated with the disorder. The physical decline of Huntington’s disease can lead to the inability to swallow, which can cause choking or aspiration. Additionally, muscle contractions can cause falls and other injuries, which can be fatal.
The cognitive decline associated with Huntington’s disease can lead to decreased awareness and judgment, which can lead to accidents or other dangerous situations. Additionally, as the disease progresses, people with Huntington’s may become unable to recognize the signs of illness and may fail to seek medical care or take prescribed medications.
Finally, Huntington’s disease can cause a weakened immune system, which can leave individuals vulnerable to infections or other illnesses, such as pneumonia or sepsis, which can be fatal.
In conclusion, death from Huntington’s disease is typically caused by a combination of physical and cognitive decline associated with the disorder, including difficulty swallowing, falls, decreased awareness, weakened immune system, and failure to seek medical care.