Ankylosing spondylitis is an inflammatory type of arthritis that affects the spine, causing eventual fusion of the spine, pain and stiffness. It is part of a group of diseases known as spondyloarthritis, which also includes psoriatic arthritis, reactive arthritis, and enteropathic arthritis.
Ankylosing spondylitis is classified as an autoimmune disorder, meaning that the body's immune system mistakenly attacks its own tissues. The exact cause of ankylosing spondylitis is unknown, but genetics play a role. HLA-B27, a gene associated with ankylosing spondylitis, is found in about 80-90% of people with the condition.
Ankylosing spondylitis is a chronic condition, meaning it is long-lasting and requires ongoing management. Treatment focuses on relieving symptoms and slowing the progression of the disease. Treatment typically includes medications, physical therapy, and lifestyle changes.