Polyglandular autoimmune syndrome type 3 (PGA-3) is a rare, genetic disorder that affects the endocrine glands and can cause a wide range of symptoms. Symptoms of PGA-3 can vary widely from person to person, and can range from mild to severe. It is important to note that the symptoms of PGA-3 can be similar to those of other autoimmune disorders, so it is important to consult a healthcare professional in order to get an accurate diagnosis.
Symptoms of Polyglandular Autoimmune Syndrome Type 3
The most common symptoms of PGA-3 include fatigue, weight loss, low blood sugar, depression, and anemia. Other potential symptoms of PGA-3 include:
• Abnormalities in the thyroid gland, such as hypothyroidism or hyperthyroidism
• Abnormalities in other endocrine glands, such as the adrenal glands, pituitary gland, or pancreas
• Infertility or menstrual irregularities
• Skin rashes or hives
• Diarrhea or constipation
• Muscle or joint pain
• Abnormal heart rhythms
• Visual disturbances
• Hearing loss
• Low blood pressure
• Abnormal levels of calcium, magnesium, or potassium in the blood
• Kidney stones or other kidney problems
• An enlarged spleen or liver
• Swelling of the lymph nodes
• Cognitive impairment
• Increased risk of infection
• Autoimmune hepatitis, which is an inflammation of the liver
It is important to note that not everyone with PGA-3 will experience all of these symptoms, and the severity of the symptoms can vary from person to person. Additionally, some people with PGA-3 may not experience any symptoms at all.