Physical exam findings in aplastic anemia can vary from patient to patient. Generally, the physical exam can reveal paleness of the skin, eyes, and mucous membranes, as well as fatigue, dyspnea, and tachycardia. Additionally, the patient may experience a weakened pulse, hypotension, and an enlarged spleen. Further physical exam findings may include petechiae, ecchymoses, lymphadenopathy, hepatomegaly, splenomegaly, and bleeding tendencies.
Patients may also have signs of anemia, such as pallor of the skin and mucous membranes, fatigue, dizziness, headache, tachycardia, dyspnea, and palpitations. The patient may experience decreased exercise tolerance, as well as an enlarged heart due to compensatory mechanisms. Additionally, the patient may experience chest pain, edema, and an enlarged liver.
Finally, the physical exam may reveal signs of infections caused by immune deficiency, such as recurrent infections, fever, and swollen lymph nodes. Other signs may include mucocutaneous manifestations, such as oral candidiasis, angular cheilitis, recurrent herpes simplex infection, and onychomycosis.
In conclusion, physical exam findings in aplastic anemia can vary widely from patient to patient. Generally, the physical exam can reveal paleness of the skin, eyes, and mucous membranes, as well as fatigue, dyspnea, tachycardia, petechiae, ecchymoses, lymphadenopathy, hepatomegaly, splenomegaly, bleeding tendencies, an enlarged heart, edema, and an enlarged liver. Additionally, the physical exam may also reveal signs of immune deficiency, such as recurrent infections, fever, and swollen lymph nodes, as well as mucocutaneous manifestations, such as oral candidiasis, angular cheilitis, recurrent herpes simplex infection, and onychomycosis.