Adult-onset Still's disease (AOSD) is a rare form of inflammatory arthritis that affects adults. It is most commonly seen in people aged 20 to 40, but it can occur at any age. It is characterized by sudden, severe episodes of fever, rash, joint pain, and fatigue. Although the cause of AOSD is not known, it is believed to be triggered by an infection or an autoimmune reaction.
Symptoms of Adult-Onset Still's Disease
The most common symptom of AOSD is a high fever that lasts for three days or more. Other symptoms include:
• Rash: A characteristic rash that appears on the trunk, arms, and legs.
• Joint pain and swelling: This is the most common symptom and can affect any joint in the body.
• Muscle pain: This is often felt as a deep, aching pain and can be felt all over the body.
• Fatigue: This is a feeling of tiredness that does not go away with rest.
• Abdominal pain: Pain in the abdomen may be due to inflammation of the liver, spleen, or other organs.
• Swollen lymph nodes: Swelling of the lymph nodes may be present.
Diagnosis of Adult-Onset Still's Disease
Diagnosis of AOSD can be difficult because its symptoms are similar to other inflammatory conditions. To diagnose AOSD, your doctor will take a detailed medical history and do a physical examination. Blood tests may also be done to look for signs of inflammation. Imaging tests, such as X-rays or MRI scans, may be used to look for joint damage.
Treatment of Adult-Onset Still's Disease
The goal of treatment for AOSD is to reduce inflammation and relieve symptoms. Treatment may include non-steroidal anti-inflammatory drugs (NSAIDs), corticosteroids, or disease-modifying antirheumatic drugs (DMARDs). In some cases, biologic medications may be used to target specific parts of the immune system. Physical therapy may be recommended to help strengthen muscles and improve joint mobility.